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Being a reputed manufacturer and exporter, we are certain to offer our clients an appreciable range of Glipizide. These drugs are used to treat type 2 diabetes by lowering the blood sugar level. In order to process these drugs, we use modern technology and quality approved ingredients at our state of the art labs as per the norm set by the health industries. Furthermore, our clients can avail Glipizide drugs from us at a reasonable price.
- Safe to consume
- Precise composition
UPAC Name : N-(4-[N-(cyclohexylcarbamoyl)sulfamoyl]phenethyl)-5-methylpyrazine-2-carboxamide
CAS Number : 29094-61-9
Innovator : Marketed by Pfizer under the brand name Glucotrol
Therapeutic Category: Antidiabetic Drug
Indication : To improve glycemic control in adults with type 2 diabetes mellitus.
Dosage: In Adult 2.5 mg/ 5mg / 10 mg
Class: Anti-diabetic drug from the sulfonylurea class
Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation sulfonylureas are both more potent and have shorter half-lives than the first-generation sulfonylureas.
Mechanism of Action:
Mechanism of action is produced by blocking potassium channels in the beta cells of the islets of Langerhans. By partially blocking the potassium channels, the cell remains depolarized, increasing the time the cell spends in the calcium release stage, which results in signaling leading to calcium influx. The increase in calcium will initiate more insulin release from each beta cell. Sulfonylureas may also cause the decrease of serum glucagon and potentiate the action of insulin at the extrapancreatic tissues.
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